| Primary Identifier | IPR034562 | Type | Domain |
| Short Name | U2B''_RRM2 |
| description | This entry represents the RNA recognition motif 2 (RRM2) of U2B". U2B"(also termed U2 snRNP B") is a unique protein that comprises the U2 snRNP. It was initially identified to bind to stem-loop IV (SLIV) at the 3' end of U2 snRNA []. Additional research indicates U2B"binds to U1 snRNA stem-loop II (SLII) as well and shows no preference for SLIV or SLII on the basis of binding affinity []. U2B"does not require an auxiliary protein for binding to RNA and its nuclear transport is independent of U2 snRNA binding. U2B"contains two RNA recognition motifs (RRMs). It also contains a nuclear localization signal (NLS) in the central domain. However, nuclear import of U2B'' does not depend on this NLS. The N-terminal RRM is sufficient to direct U2B"to the nucleus []. |
