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Protein Domain : SLIRP, RNA recognition motif

Primary Identifier  IPR034152 Type  Domain
Short Name  SLIRP_RRM
description  This entry represents the RNA recognition motif (RRM) of SLIRP, a widely expressed small steroid receptor RNA activator (SRA) binding protein, which binds to STR7, a functional substructure of SRA. SLIRP is localized predominantly to the mitochondria and plays a key role in modulating several nuclear receptor (NR) pathways. It functions as a co-repressor to repress SRA-mediated nuclear receptor co-activation. It modulates SHARP- and SKIP-mediated co-regulation of NR activity. The RNA recognition motif of SLIRP is required for SLIRP's corepression activities [].

0 Child Features

1 Parent Features

2 Protein Domain Regions