Primary Identifier | IPR034191 | Type | Domain |
Short Name | MARF1_RRM2 |
description | This entry represents the RNA recognition motif 2 (RRM2) of MARF1 (also known as Limkain-b1).MARF1 was first identified as a novel peroxisomal autoantigen that co-localizes with a subset of cytoplasmic microbodies marked by ABCD3 []. Later, it was found to be an essential protein for controlling meiosis and retrotransposon surveillance in mouse oocytes. It may function both as an adaptor to recruit specific RNA targets and an effector to catalyse the specific cleavages of target RNAs []. MARF1 contains an N-terminal NYN domain, two central RRMs, and C-terminal OST-HTH/LOTUS domains [, ]. |