| Primary Identifier | IPR000493 | Type | Family |
| Short Name | InsP3_rcpt |
| description | The inositol 1,4,5-trisphosphate (IP3)3 receptors (IP3R) are tetrameric intracellular Ca2 release channels on the endoplasmic membrane that are activated by the ligand IP3 []. The mammalian IP3R family consists of three isoforms (IP3R1, IP3R2, and IP3R3). They form homotetrameric or heterotetrameric channels []. They contain three functional domains: an N-terminal IP3-binding domain, a channel-forming domain localized to the C terminus, and a regulatory/coupling domain connecting these two domains []. |
