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Protein Domain : Calcium release-activated calcium channel protein

Primary Identifier  IPR012446 Type  Family
Short Name  CRAC_channel
description  This entry includes Drosophila Orai and human Orai1, Orai2 and Orai3. ORAI-1 green fluorescent protein (GFP) reporters are co-expressed with STIM-1 (ER CA(2+) sensors) in the gonad and intestine. The protein has four predicted transmembrane domains with a highly conserved region between TM2 ad TM3. This conserved domain is thought to function in channel regulation. ORAI1-related proteins are required for the production of the calcium channel, CRAC, along with STIM1-related proteins [].
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2 Child Features

Trail: ProteinDomain

0 Parent Features

22 Protein Domain Regions

Trail: ProteinDomain




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