| Primary Identifier | IPR029727 | Type | Family |
| Short Name | MME/CD10/NEP |
| description | Neprilysin (also known as MME, NEP or CD10) is a membrane metallo-endopeptidase acting on polypeptides of up to 30 amino acids. It degrades the amyloid β-peptide (Abeta) in the central nervous system, which is associated with Alzheimer's disease []. It was identified in leukemia as a tumour-specific antigen (common acute lymphoblastic leukemia antigen) and is used in cancer diagnosis []. It plays an important role in inflammatory responses []. In mammals, it is involved in mammary gland development []. |
