| Primary Identifier | IPR042717 | Type | Domain |
| Short Name | MLCK2_STKc |
| description | STKs (serine/threonine kinases) catalyse the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. MLCK2 (or MYLK2) phosphorylates myosin regulatory light chain and controls the contraction of skeletal muscles []. It is a key regulator of cardiac contraction []. MLCK2 contains a single kinase domain near the C terminus followed by a regulatory segment containing an autoinhibitory Ca2 /calmodulin binding site. |
