| Primary Identifier | IPR022116 | Type | Domain |
| Short Name | P1_N |
| description | This domain is found at the N-terminal of adhesins and hypothetical adhesin-like proteins from Mycoplasma pneumoniae and Mycoplasma genitalium, including adhesin P1 which was first identified as the major determinant for cytoadherence and gliding motility in M. pneumoniae [, ]. P1 forms a transmembrane adhesion complex with P40/P90, called 'Nap', which mediates motility and infectivity in these organisms. It consists of a large N-terminal domain that adopts a β-propeller topology and a smaller, more conserved C-terminal domain followed by a transmembrane domain. The C-terminal domain acts as a stalk connecting the large N-terminal domain with the outer surface of the cell membranes [, ]. |
