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Protein Domain : Oxysterol-binding protein

Primary Identifier  IPR000648 Type  Family
Short Name  Oxysterol-bd
description  A number of eukaryotic proteins that seem to be involved with sterol synthesis and/or its regulation have been found []to be evolutionary related. These include mammalian oxysterol-binding protein (OSBP), a protein of about 800 amino-acid residues that binds a variety of oxysterols (oxygenated derivatives of cholesterol) [, ]; yeast Osh1, a protein of 859 residues that also plays a role in ergosterol synthesis []; yeast proteins Hes1 and Kes1, highly related proteins of 434 residues that seem to play a role in ergosterol synthesis [, ]; Probable transporter efuK from the fungi Hormonema carpetanum, which is involved in the biosynthesis of enfumafungin [[cite30051576]]; and OSBP-related proteins (ORP) from plants such as Arabidopsis thaliana [].

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152 Protein Domain Regions