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Protein Domain : Smad anchor for receptor activation, Smad-binding domain

Primary Identifier  IPR024608 Type  Domain
Short Name  SARA_Smad-bd
description  Smad proteins mediate transforming growth factor-beta (TGF-beta) signaling from the transmembrane serine-threonine receptor kinases to the nucleus. SARA (Smad anchor for receptor activation) recruits Smad2 to the TGF-beta receptors for phosphorylation [].This entry represents the Smad-binding domain (SBD) of SARA. This domain consists of a rigid coil, an alpha helix, and a beta strand, and interacts with Smad2 [].
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3 Protein Domain Regions

Trail: ProteinDomain




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