Primary Identifier | IPR010050 | Type | Family |
Short Name | MTA_SAH_nuc_hyp |
description | This entry represents the enzyme 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, which acts on its two substrates at the same active site, from the Rhizobiales (alphaproteobacteria).This clade of sequences is sufficiently distinct from the characterised proteins [, ]which form as to cast some doubt on the accuracy of annotations based on sequence similarity alone. This enzyme is involved in the recycling of the components of S-adenosylmethionine after it has donated one of its two non-ribose sulphur ligands to an acceptor. In the case of 5'-methylthioadenosine this represents the first step of the methionine salvage pathway in bacteria [, ]. This enzyme is widely distributed in bacteria. |