| Primary Identifier | IPR010089 | Type | Family |
| Short Name | Flavoprotein_WrbA-like |
| description | WrbA (tryptophan (W) repressor-binding protein) was discovered in Escherichia coli, where it was proposed to play a role in regulation of the tryptophan operon [], which has been put in question since then []. Instead, WrbA has been shown to have FMN-dependent NAD(P)H:quinone oxidoreductase acivity [, ]. A role in quinone detoxification has been proposed, supported by evidence suggesting its involvement in oxidative defense and/or cell signaling [, ].This entry also includes QR2 from Triphysaria versicolor. QR2 acts as a NAD(P)H:quinone oxidoreductase reducing quinones by a two-electron transfer mechanism []. |
