| Primary Identifier | IPR022047 | Type | Family |
| Short Name | Microcephalin-like |
| description | Microcephalin is implicated in chromosome condensation and DNA damage induced cellular responses [, ]. It may play a role in neurogenesis and regulation of the size of the cerebral cortex in animals. It is a protein, which if expressed homozygously, causes the organism to have the condition microcephaly - a drastically reduced brain mass and volume []. Microcephalin is predicted to contain three BRCA1 C-terminal domains, the first of which is the probable microcephaly mutation site. This entry includes non-mammalian uncharacterised proteins (from lower vertebrates and fungi) related to microcephalin. |
