| Primary Identifier | IPR024933 | Type | Family |
| Short Name | TFP11 |
| description | Septin and tuftelin interacting proteins (STIPs) are G-patch domain proteins involved in spliceosome disassembly []. The mouse protein, known as TFT11 was originally identified as a protein interacting with tuftelin, one of the presumed enamel matrix proteins []. The Drosophila protein STP1 was originally identified as a septin-interacting protein []. In both cases these interactions were identified by a yeast two-hybrid system and their function and direct physical association were not characterised. Subsequent studies show that these proteins are widely expressed and function as splicing factors [, ]. STIP is essential for embryogenesis in Caenorhabditis elegans []. |
