| Primary Identifier | IPR010334 | Type | Family |
| Short Name | Dcp1 |
| description | An essential step in mRNA turnover is decapping. In yeast, two proteins have been identified that are essential for decapping, Dcp1 (this family) and Dcp2. Dcp1 is a coactivator that binds to the decapping enzyme Dcp2 and forms a decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation []. Yeast Dcp1 interact directly with Dcp2, however, the Dcp1-Dcp2 interaction is promoted by an additional factor, EDC4 []. In the nervous system, it promotes neurons' lifespan through the negative regulation of the insulin-like peptide ins-7 expression []. |
