| Primary Identifier | IPR035875 | Type | Domain |
| Short Name | BMX_SH2 |
| description | Cytoplasmic tyrosine-protein kinase BMX (bone marrow tyrosine kinase gene on chromosome X, also known as ETK) is a non-receptor tyrosine kinase (). It plays central but diverse modulator roles in various signalling processes involved in the regulation of actin reorganisation, cell migration, cell proliferation and survival, cell adhesion, and apoptosis [, , ]. It has a role in inflammation, cardiovascular disease, and cancer []. It is activated downstream of phosphatidylinositol-3 kinase (PI3K) and the kinase Src [].This entry represents the SH2 domain of BMX. |
