Primary Identifier | IPR020440 | Type | Family |
Short Name | IL-17_chr |
description | Interleukins (IL) are a group of cytokines that play an important role in the immune system. They modulate inflammation and immunity by regulating growth, mobility and differentiation of lymphoid and other cells. Interleukin-17 (IL-17) is a potent proinflammatory cytokine produced by activated memory T cells []. The IL-17 family (of which there are 6 known members, termed IL-17A to IL-17F) is thought to represent a distinct signalling system that appears to have been highly conserved across vertebrate evolution []. Family members play an active role in inflammatory diseases, autoimmune diseases and cancer []. This entry represents interleukin-17 found in chordata. |