Primary Identifier | IPR032928 | Type | Family |
Short Name | ETS_V1 |
description | This transcriptional activator is known as ETS translocation variant 1 (ETV1) or Ets-related protein 81 (ER81). It is a member of the larger E-twenty six (Ets) family whose members bind DNA directly via a conserved Ets domain []. ETV1 contributes to the formation of dopaminergic neurons []and also contributes to formation of proper connections between group 1a sensory afferents and motor neurons []. It is an oncoprotein implicated in Ewing tumours and different types of cancer [, ]. |