Primary Identifier | IPR046398 | Type | Family |
Short Name | YFT2 |
description | This family represents a group of fungal proteins which belongs to the Fat storage-inducing transmembrane protein family (FITM), including acyl-coenzyme A diphosphatase YFT2 from Saccharomyces cerevisiae, the yeast orthologue of human FIT2 []. This protein is required for ER membrane biosynthesis in response to ER stress, for maintaining ER structure and for lipid droplets (LDs) biogenesis []. YFT2 may support directional budding of nascent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation [, ]. |