| Primary Identifier | IPR046378 | Type | Domain |
| Short Name | DAXX_histone-bd |
| description | Daxx (also known as death domain-associated protein 6) is a nuclear protein that modulates transcription of various genes and is involved in cell death and/or the suppression of growth. Daxx is also a histone chaperone conserved in metazoa that acts specifically on histone H3.3. This entry represents the histone-binding domain of Daxx that interacts with the histone H3.3-H4 dimer, and in doing so competes with DNA binding and interactions between the histone chaperone ASF1/CIA and the H3-H4 dimer [, , , , , ]. |
