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Protein Domain : Protein FosB

Primary Identifier  IPR029813 Type  Family
Short Name  FosB
description  Transcription factor activator protein (AP)-1, comprising Jun (c-Jun, JunB, and JunD) and Fos (c-Fos, FosB, Fra1, and Fra2) family members, plays a central role in regulating gene transcription in various biological processes []. Fos protein family members form stable heterodimerswith Jun proteins and thereby enhance their DNA-bindingactivity []. This entry reprsents FosB []. FosB-null mice display impaired adult hippocampal neurogenesis and spontaneous epilepsy with depressive behavior [].

0 Child Features

1 Parent Features

13 Protein Domain Regions