Primary Identifier | IPR029818 | Type | Family |
Short Name | p21SNFT |
description | Basic leucine zipper transcriptional factor ATF-like 3 (B-ATF-3, also known as p21SNFT) is a AP-1 family transcription factor that can replace Fos in dimerisation with Jun on a consensus AP-1 binding site (12-O-tetradecanolyphorbol-13-acetate response element (TRE)) and interact with Jun and NF-AT at the distal NF-AT/AP-1 enhancer element []. It may repress transcriptional activity by inducing a unique conformation in the transcription factor complex [, ]. It controls the differentiation of CD8+ thymic conventional dendritic cells in the immune system []. |