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Protein Domain : Jun dimerization protein 2

Primary Identifier  IPR029819 Type  Family
Short Name  JDP2
description  Jun dimerization protein 2 (JDP2) regulates the AP-1-mediated activation of transcription []. It can either form homodimers or form heterodimers with other AP-1 members, such as c-Jun, JunB, JunD, and ATF-2 []. It binds directly to histones and DNAs and then inhibits the p300-mediated acetylation both of core histones and of reconstituted nucleosomes that contain JDP2 recognition DNA sequences []. JDP2 plays important roles in cellular differentiation, ageing and cancer [, ].

0 Child Features

1 Parent Features

4 Protein Domain Regions