Primary Identifier | IPR009269 | Type | Domain |
Short Name | NKAP_C |
description | This is the C-terminal domain found in NF-kappa-B-activating protein (Nkap) and a hypothetical open reading frame on chromosome 6, c6orf194. It is the HDAC3 binding domain required for transcriptional repression []. Nkap functions as a transcriptional repressor on Notch target genes, and is required for T cell development and acquisition of functional competency [, , ]. |