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Protein Domain : PRP6, TPR-like domain

Primary Identifier  IPR063732 Type  Domain
Short Name  PRP6_TPR
description  This entry represents a TPR repeat domain found in human pre-mRNA splicing factor 6 (PRP6), Crooked neck-like protein 1 from Danio rerio and similar proteins found in eukaryotes. PRP6 is involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. It enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation [, , ].

0 Child Features

0 Parent Features

1 Protein Domain Regions