| Primary Identifier | IPR017250 | Type | Family |
| Short Name | Hist_deAcase_cplx_SAP18 |
| description | Histone acetylation plays a key role in the regulation of gene expression. The chromatin structure and accessibility of genes to transcription factors isregulated by enzymes that acetylate and deacetylate histones. The Sin3A-histone deacetylase (HDAC) co-repressor complex consists of multiple proteins and regulates gene expression by deacetylating histones.This group represents the Histone deacetylase complex subunit SAP18 (Sin3A associated protein 18) []. SAP18 adopts an ubiquitin-like fold with several large loop insertions []. |
