Primary Identifier | IPR022542 | Type | Domain |
Short Name | FOCAD/RST1_DUF3730 |
description | This domain of unknown function is found in Focadhesin from animals and RST1 (RESURRECTION 1) from plants. Focadhesin (FOCAD) is a focal adhesion protein with potential tumour suppressor function in gliomas []. RST1 was originally identified in a genetic screen for factors involved in the biosynthesis of epicuticular waxes []. Later, RST1 and RST1 INTERACTING PROTEIN (RIPR) have been shown to act as cofactors of the cytoplasmic exosome and the Ski complex in plants []. RST1 is involved in the suppression of siRNA-mediated silencing of transgenes and certain endogenous transcripts []. |