Primary Identifier | IPR034566 | Type | Family |
Short Name | MTOPVIB_plant |
description | MTOPVIB (meiotic topoisomerase VIB-like) is a structural homologue of the archaeal topo VIB subunit []. MTOPVIB forms a complex with the two Arabidopsis thaliana SPO11 orthologues (SPO11-1 and SPO11-2) and is essential for meiotic DSB formation []. The SPO11 protein catalyzes the formation of meiotic DNA double strand breaks (DSBs) and it is the eukaryotic homologue of the archaeal DNA topoisomerase VIA. |