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Protein Domain : Meiosis-specific kinetochore protein

Primary Identifier  IPR034545 Type  Family
Short Name  Meikin
description  The meiosis-specific kinetochore factor Meikin plays a crucial role in both mono-orientation and centromeric cohesion protection during meiosis I, partly by stabilizing the localization of the cohesin protector shugoshin, and also by recruiting Polo-like kinase PLK1 to the kinetochores. PLK1 is required for mono-orientation and the protection of centromeric cohesion [].

0 Child Features

0 Parent Features

3 Protein Domain Regions