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Protein Domain : Endosomal/lysomomal potassium channel TMEM175

Primary Identifier  IPR010617 Type  Family
Short Name  TMEM175
description  In animals, TMEM175 is an organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. It forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. TMEM175 is the major lysosomal K+ conductance [, ].This entry also includes TMEM175 homologues from bacteria and archaea.

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5 Protein Domain Regions