| Primary Identifier | IPR009447 | Type | Family |
| Short Name | PIGW/GWT1 |
| description | Glycosylphosphatidylinositol (GPI) is a conserved post-translational modification to anchor cell surface proteins to plasma membrane in eukaryotes. PIGW and the yeast homologue GWT1 are involved in the addition of the acyl-chain to inositol in an early step of GPI biosynthesis []. Mutations in PIGW are associated with West syndrome and hyperphosphatasia with mental retardation syndrome []. |
