| Primary Identifier | IPR034450 | Type | Family |
| Short Name | ADIRF |
| description | APM2 (adipose specific 2 or adipose most abundant 2), also known as adipogenesis regulatory factor, was so named because it was originally identified as the second most abundant transcript in adipose tissue []. It up-regulates the levels of CCAAT/enhancer binding protein alpha (C/EBP-alpha) and PPAR-gamma, and promotes adipogenic differentiation starting from the early stage of adipogenesis. It is thought to be an adipocyte lineage-specific nuclear factor that can modulate the master adipogenesis transcription factors early during differentiation []. It is also involved in regulating glucose transport in adipocytes, as well as regulating the number of preadipocytes [].APM2 it is widely dysregulated in various cancers []. |
