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Protein Domain : Conserved oligomeric Golgi complex subunit 6

Primary Identifier  IPR010490 Type  Family
Short Name  COG6
description  COG6 is a component of the peripheral membrane COG (conserved oligomeric Golgi) complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, regulates tethering of retrograde intra-Golgi vesicles and is required for normal Golgi morphology and localisation [, , ]. COG subunits belong to the CATCHR (complexes associated with tethering containing helical rods) family which includes subunits of the GARP/EARP, exocyst, and Dsl1 complexes, all evolutionary related and have a conserved structural fold consisting of α-helical bundles in tandem at the C-terminal and a coiled-coil region at the N-terminal [, ].

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14 Protein Domain Regions