| Primary Identifier | IPR046468 | Type | Domain |
| Short Name | Spt20-like_SEP |
| description | This entry represents the SEP domain found in Spt20 from yeast and human [, , ]. The Spt20 protein is part of the SAGA complex which is a large complex mediating histone deacetylation. Yeast Spt20 has been shown to play a role in structural integrity of the SAGA complex as as no intact SAGA could be purified in spt20 deletion strains. Spt20 is indispensable under endoplasmic reticulum (ER) stress conditions, being involved in the regulation of stress-responsive genes transcription. This domain interacts with LisH motif helices of Taf5 []. This domain is also found in Protein PHYTOCHROME-DEPENDENT LATE-FLOWERING (PHL), which is involved in the phytochrome B-dependent regulation of flowering [, , ]. |
