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Protein Domain : Macrophage-capping protein

Primary Identifier  IPR029917 Type  Family
Short Name  CapG
description  Macrophage-capping protein (CapG) belongs to the Villin/Gelsolin family, whose members are Ca(2+)-dependent, multidomain regulators of the actin cytoskeleton []. CapG was first isolated from alveolar macrophages as an actin-modulating protein that reversibly cap the barbed ends of actin filaments []. Unlike most of the Villin/Gelsolin family members, it does not sever actin filaments []. It is involved in cell invasion and metastasis in several cancers [, ].

0 Child Features

1 Parent Features

11 Protein Domain Regions