| Primary Identifier | IPR029919 | Type | Family |
| Short Name | FliI |
| description | Protein flightless-1 (FliI) was first identified in the Drosophila melanogaster []. It belongs to the Villin/Gelsolin family, whose members are actin-modulating proteins that sever F-actin, cap the barbed ends of actin filaments preventing monomer exchange, and promote the nucleation step of actin polymerisation [].This entry represent FliI and its homologues. FliI may serve as a nuclear receptor coactivator []and is involved in embryonic development []. In mouse fibroblasts it caps actin filaments and localises to focal adhesions, which collectively affect focal adhesion maturation []. |
