|  Help  |  About  |  Contact Us

Protein Domain : Replication factor-A protein 1, N-terminal

Primary Identifier  IPR007199 Type  Domain
Short Name  Rep_factor-A_N
description  Replication factor-a protein 1 (RPA1) forms a multiprotein complex with RPA2 and RPA3 that binds single-stranded DNA and functions in the recognition of DNA damage for nucleotide excision repair. The complex binds to single-stranded DNA sequences participating in DNA replication in addition to those mediating transcriptional repression and activation, and stimulates the activity of cognate strand exchange protein Sep1. It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the Simian Virus 40 origin of replication [].

0 Child Features

0 Parent Features

6 Protein Domain Regions