| Primary Identifier | IPR007174 | Type | Family |
| Short Name | Las1 |
| description | Las1 is an endoribonuclease responsible for cleavage at the C2 site during pre-rRNA processing []. It interacts with Grc3 polynucleotide kinase and is required for ribosome synthesis []. Las1-mediated C2 cleavage depends on the functional integrity of the associated Grc3 phosphotransferase, while phosphorylation of the 26S pre-rRNA by Grc3 relies on a functionally competent Las1 nuclease [, ]. |
