| Primary Identifier | IPR044113 | Type | Domain |
| Short Name | DEADc_DDX41 |
| description | DDX41 interacts with several spliceosomal proteins and may recognise the bacterial second messengers cyclic di-GMP and cyclic di-AMP, resulting in the induction of genes involved in the innate immune response []. DDX41 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. Mutations of the DDX41 gene cause myeloproliferative/lymphoproliferative neoplasms, familial (MPLPF) [].This entry represents the DEAD-box domain of DDX41. It contains the ATP-binding region []. |
