| Primary Identifier | IPR034780 | Type | Family |
| Short Name | SLTM |
| description | SLTM belongs to the scaffold attachment factor B (SAFB) family. When overexpressed, it acts as a general inhibitor of transcription that eventually leads to apoptosis [, ].Scaffold attachment factor B (SAFB) family members include SAFB1, SAFB2 and SAFB-like transcriptional modulator, SLTM. They contain an N-terminal DNA-binding (SAF-A/B, Acinus and PIAS, SAP) domain, an RNA-binding domain (RBD) and an C-terminal arginine/glycine motif RGG/RG domain. Their RGG/RG domain, which partially overlaps with a putative coiled-coil domain, is most conserved and is likely to be involved in protein-protein interactions []. |
