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Protein Domain : DNA polymerase V/Myb-binding protein 1A

Primary Identifier  IPR007015 Type  Family
Short Name  DNA_pol_V/MYBBP1A
description  Proteins of this family are predominantly nucleolar. Myb-binding protein 1A (MYBBP1A) is a transcription regulator that may play an important role in the cellular stress response [, , , ]. This family also includes the fifth essential DNA polymerase (Pol5p) of Schizosaccharomyces pombe (Fission yeast) and Saccharomyces cerevisiae (Baker's yeast) (). Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units []. This protein was originally thought to be a DNA polymerase, however, later reseach indicated its involvement in ribosome assembly [, ].

0 Child Features

0 Parent Features

9 Protein Domain Regions