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Protein Domain : tRNA methyltransferase 10 homologue C

Primary Identifier  IPR025812 Type  Family
Short Name  TRM10C
description  Mitochondrial RNase P (mtRNase P) cleaves tRNA molecules in their 5'-ends and consists of 3 components: a tRNA methyltransferase (MRPP1/TRMT10), a dehydrogenase/reductase-family member (MRPP2/HSD17B10), and MRPP3 (KIAA03910) [].This entry represents tRNA methyltransferase 10 homologue C (TRMT10C), which is a metazoa homologue to yeast TRM10, a tRNA m1G methyltransferase responsible for modification at position 9. In humans there are three TRM10 orthologues. Mutations in TRMT10C cause mitochondrial disease [].

0 Child Features

1 Parent Features

1 Protein Domain Regions