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Protein Domain : Conserved oligomeric Golgi complex subunit 7

Primary Identifier  IPR019335 Type  Family
Short Name  COG7
description  The conserved oligomeric Golgi (COG) complex is an eight-subunit (Cog1-8) peripheral Golgi protein involved in membrane trafficking and glycoconjugate synthesis []. COG7 is required for normal Golgi morphology and trafficking. Defects in COG7 are the cause of congenital disorder of glycosylation type 2E (CDG2E). CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation [].

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6 Protein Domain Regions