Primary Identifier | IPR046800 | Type | Domain |
Short Name | Plexin_RBD |
description | This entry represents the RhoGTPase-binding domain found in the cytoplasmic domain of plexins [, ]. Plexins are receptors for semaphorins, and plexin signalling is important in pathfinding and patterning of both neurons and developing blood vessels [, ]. The cytoplasmic region, which has been called a SEX domain [], and is involved in downstream signalling pathways, by interaction with proteins such as Rac1, RhoD, Rnd1 and other plexins []. |