| Primary Identifier | IPR006226 | Type | Family |
| Short Name | Mtu_PIN |
| description | Members of this family are VapC proteins that consist almost entirely of a PIN (PilT N terminus) domain. This family was originally defined a set of twelve closely related paralogs found in Mycobacterium tuberculosis, but additional members are found now Synechococcus sp. WH8102, etc. This family includes ribonucleases VapC24 and Vap25 among others. They are the toxic component of a toxin-antitoxin (TA) module. They act as an RNase and all their toxic effects are neutralised by coexpression with cognate antitoxin []. |
