| Primary Identifier | IPR033960 | Type | Family |
| Short Name | EXOC5/Sec10 |
| description | The exocyst is a highly conserved complex composed of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, and Exo84, which was originally identified in Saccharomyces cerevisiae []. Mammalian homologues of all eight exocyst proteins have been identified []. The exocyst is required for exocytosis; it mediates tethering of the secretory vesicle before docking and fusion with the plasma membrane [].Sec10 (also known as exocyst complex component 5) is a component of the eukaryotic exocyst complex. It modulates the synthesis and delivery of secretory and basolateral plasma membrane proteins [, ], and is necessary for primary ciliogenesis and cystogenesis [, ]. |
