| Primary Identifier | IPR007303 | Type | Family |
| Short Name | TIP41-like |
| description | In budding yeast, TIP41 interacts with TAP42 to regulate protein phosphatase activity []. In mammalian cells, TIP41-like protein (TIPRL) does not directly bind TAP42, but rather primarily interacts with PP2A, PP4 or PP6 catalytic subunits. TIPRL inhibits PP4 activity to allow for H2AX phosphorylation and the subsequent DNA damage response []. |
