| Primary Identifier | IPR044538 | Type | Family |
| Short Name | Vta1-like |
| description | This entry represents yeast Vta1 and its homologues from animals and plants. Vta1 interacts with the AAA ATPase Vps4 and is required for multivesicular body (MVB) sorting [, ]. This entry also includes LIP5 from Arabidopsis. LIP5 is a positive regulator of the Suppressor of K(+) Transport Growth Defect1 (SKD1) AAA ATPase in MVB biogenesis. It is also a target of pathogen-responsive mitogen-activated protein kinases (MPKs) and plays a critical role in plant basal resistance [, ]. Mammalian Vta1 homologue functions in MVB sorting and is required for HIV release []. |
