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Protein Domain : CRC domain-containing protein TSO1-like

Primary Identifier  IPR044522 Type  Family
Short Name  TSO1-like
description  This entry represents a group of CRC domain-containing proteins, including TSO1 and TCX2/3/4 from Arabidopsis. They are are homologues of the LIN54 DNA-binding components of the mammalian DREAM complex, a protein complex responsible for the regulation of cell cycle-dependent gene expression. TSO1 has been shown to regulate meristem organization and cell division [, ]. It may transcriptionally represses MYB3R1 (a conserved cell cycle regulator), and together they coordinate cell proliferation with differentiation in shoot and root []. TCX3 (also known as SOL1) and TCX2 (also known as SOL2) have been shown to regulate fate transition and cell divisions in the Arabidopsis stomatal lineage [].

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