| Primary Identifier | IPR044518 | Type | Family |
| Short Name | ARF_GAP_AGD11/12/13 |
| description | This entry represents a group of plant ADP-ribosylation factor GTPase-activating proteins (ArfGAPs), such as AGD11/12/13 from Arabidopsis. ArfGAPs are a family of proteins containing an ArfGAP catalytic domain that induces the hydrolysis of GTP bound to the small guanine nucleotide-binding protein Arf, a member of the Ras superfamily of GTPases. Of all known members belonging to the ARF-GAP protein family only AGD11, 12, and 13 possess a C2 domain enabling them to bind phospholipids, phosphoinositide and proteins in a calcium-dependent manner []. The C-terminal domain of AGD12 is structurally related to ENHANCED BENDING (EHB) 1, and both of them function as calcium-dependent proteins that affect gravitropism in Arabidopsis thaliana []. |
